Jackson was infected by a crafted brain parasite that was feeding off his cerebral activity.
Jackson believes that he was infected by a fellow guild member, Orion Malaver. Jefferson had become suspicious that Malaver was steering the guild into fruitless actions.
Malavar died under mysterious circumstances shortly after Jefferson was infected. The house of Malaver then fell into decline and no longer exists.
Jackson had discovered that the motes could act in unison and showed signs of intelligence when in this state.